Test: Serum IgE Test - Grass - Bremuda

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Background/Purpose

Grass pollen is a major cause of respiratory allergy worldwide. Grasses are botanically classified in the family of Gramineae and in particular in the subfamily of Pooideae, which includes the species most commonly responsible of allergic sensitisation, such as Anthoxantum odoratum, Dactylis glomerata, Festuca elatior, Holcus lanatus, Lolium perenne, Phleum pratense, and Poa pratensis. Another species causing respiratory allergy is Cynodon dactylon, which belongs to the subfamily of Panicoideae. These species have variable importance in different geographical areas. In Europe, Dactylis glomerata, Poa pratensis, Lolium perenne and Anthoxantum odoratum are homogeneously distributed, while Phleum pratense is the dominant grass in Northern regions and in the United Kingdom, and Cynodon dactylon is present only in Southern regions [. To date, more than 150 allergens from 52 grass species are known, classified in 13 groups according to similar physicochemical and immunologic properties . Among these allergens, the molecules from Phleum pratense Phl p 1, Phl p 2, Phl p 5, and Phl 6, and their homologous in other grasses, are known as major allergens.

Procedure

A blood sample is obtained from the patient, typically from a venipuncture.
The sample is stored in a red cap vile.
Testing is performed in a lab using an ELISA analyzer or similar technology.
Performed: Bilaterally

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Serum specific IgE Test - Grass - Bermuda

Criteria

• Low reading on scale

Measurement

LOINC Code

6041-8

Scale/Grading

selection range; grade - LOINC ID
Option - Value option selection range; grade - LOINC IDNegative < 0.01 ; Pass - LA6111-4Equivocal-Low between 0.1-0.31 ; Fail - LA6112-2Low between 0.32-0.55 ; Fail - LA6113-0Moderate between 0.56-1.4 ; Fail - LA6114-8High between 1.4-3.9 ; Fail - LA6115-5Very High between 3.91-19 ; Fail - LA10137-0Extremely High > 19 ; Fail - LA10138-8